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Science and Technology/Engineering > Grade High School > Biology

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Science and Technology/Engineering | Grade : High School

Discipline - Biology

Core Idea - Heredity: Inheritance and Variation of Traits

[HS.LS.3.2] - Make and defend a claim based on evidence that genetic variations (alleles) may result from (a) new genetic combinations via the processes of crossing over and random segregation of chromosomes during meiosis, (b) mutations that occur during replication, and/or (c) mutations caused by environmental factors. Recognize that mutations that occur in gametes can be passed to offspring. Clarification Statement: Examples of evidence of genetic variation can include the work of McClintock in crossing over of maize chromosomes and the development of cancer due to DNA replication errors and UV ray exposure. State Assessment Boundary: Specific phases of meiosis or identification of specific types of mutations are not expected in state assessment.


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Predecessor Standards:

  • 8.LS.3.1
    Develop and use a model to describe that structural changes to genes (mutations) may or may not result in changes to proteins, and if there are changes to proteins there may be harmful, beneficial, or neutral changes to traits. Clarification Statements: An example of a beneficial change to the organism may be a strain of bacteria becoming resistant to an antibiotic. A harmful change could be the development of cancer; a neutral change may change the hair color of an organism with no direct consequence. State Assessment Boundary: Specific changes at the molecular level (e.g., amino acid sequence change), mechanisms for protein synthesis, or specific types of mutations are not expected in state assessment.

Successor Standards:

No Successor Standards found.

Same Level Standards:

  • WCA.9-10.7
    Conduct short as well as more sustained research projects to answer a question (including a self-generated question) or solve a problem; narrow or broaden the inquiry when appropriate; synthesize multiple sources on the subject, demonstrating understanding of the subject under investigation.
  • HS.LS.3.1
    Develop and use a model to show how DNA in the form of chromosomes is passed from parents to offspring through the processes of meiosis and fertilization in sexual reproduction. Clarification Statement: The model should demonstrate that an individual’s characteristics (phenotype) result, in part, from interactions among the various proteins expressed by one’s genes (genotype). State Assessment Boundary: Identification of specific phases of meiosis or the biochemical mechanisms involved are not expected in state assessment.
  • HS.LS.3.4
    Use scientific information to illustrate that many traits of individuals, and the presence of specific alleles in a population, are due to interactions of genetic factors and environmental factors. Clarification Statements: Examples of genetic factors include the presence of multiple alleles for one gene and multiple genes influencing a trait. An example of the role of the environment in expressed traits in an individual can include the likelihood of developing inherited diseases (e.g., heart disease, cancer) in relation to exposure to environmental toxins and lifestyle; an example in populations can include the maintenance of the allele for sickle-cell anemia in high frequency in malaria-affected regions because it confers partial resistance to malaria. State Assessment Boundary: Hardy-Weinberg calculations are not expected in state assessment.