Science and Technology/Engineering | Grade : High School
Discipline - Biology
Core Idea - Heredity: Inheritance and Variation of Traits
[HS.LS.3.1] - Develop and use a model to show how DNA in the form of chromosomes is passed from parents to offspring through the processes of meiosis and fertilization in sexual reproduction. Clarification Statement: The model should demonstrate that an individual’s characteristics (phenotype) result, in part, from interactions among the various proteins expressed by one’s genes (genotype).
State Assessment Boundary: Identification of specific phases of meiosis or the biochemical mechanisms involved are not expected in state assessment.
[RCA-ST.9-10.7] -
Translate quantitative or technical information expressed in words in a text into visual form (e.g., a table or chart) and translate information expressed visually or mathematically (e.g., in an equation) into words.
[WCA.9-10.1] -
Write arguments focused on discipline-specific content.
[HS.LS.1.1] -
Construct a model of transcription and translation to explain the roles of DNA and RNA that code for proteins that regulate and carry out essential functions of life. Clarification Statements: Proteins that regulate and carry out essential functions of life include enzymes (which speed up chemical reactions), structural proteins (which provide structure and enable movement), and hormones and receptors (which send and receive signals). The model should show the double-stranded structure of DNA, including genes as part of DNA’s transcribed strand, with complementary bases on the non-transcribed strand. State Assessment Boundaries: Specific names of proteins or specific steps of transcription and translation are not expected in state assessment. Cell structures included in transcription and translation will be limited to nucleus, nuclear membrane, and ribosomes for state assessment.
[HS.LS.1.4] -
Construct an explanation using evidence for why the cell cycle is necessary for the growth, maintenance, and repair of multicellular organisms. Model the major events of the cell cycle, including (a) cell growth and DNA replication, (b) separation of chromosomes (mitosis), and (c) separation of cell contents. State Assessment Boundary: Specific gene control mechanisms or specific details of each event (e.g., phases of mitosis) are not expected in state assessment.
[HS.LS.3.2] -
Make and defend a claim based on evidence that genetic variations (alleles) may result from (a) new genetic combinations via the processes of crossing over and random segregation of chromosomes during meiosis, (b) mutations that occur during replication, and/or (c) mutations caused by environmental factors. Recognize that mutations that occur in gametes can be passed to offspring. Clarification Statement: Examples of evidence of genetic variation can include the work of McClintock in crossing over of maize chromosomes and the development of cancer due to DNA replication errors and UV ray exposure. State Assessment Boundary: Specific phases of meiosis or identification of specific types of mutations are not expected in state assessment.